"A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." ? Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene
Advances in RNA-sequencing (RNA-seq) technologies have provided an unprecedented opportunity to explore the gene expression landscape across individuals, tissues, and environments by efficiently profiling the RNA sequences present in the samples. When a reference genome sequence or a transcriptome of the sample is available,...
Leland H. Hartwell Director, Fred Hutchinson Cancer Research Center, Nobel Laureate for Medicine, 2001 Yeast has proved to be the most useful single-celled organism for studying the fundamental aspects of cell biology. Resources are now available for yeast that greatly simplify and empower new investigations, like the presence of strains with...
Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder affecting 5–10% of children and adolescents and 3% of adults. Attention Deficit Hyperactivity Disorder: From Genes to Patients aims to provide a comprehensive, state-of-the-art overview of the critical aspects of ADHD, and hopefully will serve as...
The rapidly growing amount of data, available from different technologies in the field of bio-sciences, high-energy physics, economy, climate analysis, and in several other scientific disciplines, requires a new generation of machine learning and statistical methods to deal with their complexity and heterogeneity. As data collections becomes...
"Paul Nahin's Digital Dice is a marvelous book, one that is even better than his Duelling Idiots. Nahin presents twenty-one great probability problems, from George Gamow's famous elevator paradox (as corrected by Donald Knuth) to a bewildering puzzle involving two rolls of toilet paper, and he solves them all with the aid...
The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization.
Prediction of Protein Structures, Functions and Interactions presents...
Brain tumors have a longstanding reputation for being intractable to therapy, and with evidence suggesting that the incidence of some brain tumors is increasing, this has become the most feared cancer. However, with improvements in imaging technologies, radiation therapy and chemotherapy , as well as a greater knowledge of the genetic causes...
Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology...
This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of...
Data mining and data modeling are hot topics and are under fast development. Because of its wide applications and rich research contents, a lot of practitioners and academics are attracted to work on these areas. In the view of promoting the communications and collaborations among the practitioners and researchers in Hong Kong, a two-day...
Wiley Series on Bioinformatics: Computational Techniques and Engineering
Discover how data mining is fueling new discoveries in bioinformatics
As the field of bioinformatics continues to flourish, producing enormous amounts of new data, the need for sophisticated methods of data mining to better manage and extract meaning from...
