It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text...

Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular...

Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology...

In addition to communicating current methods for diagnosis and assessing the array of conventional and newfound therapeutic options for dry eye and ocular surface disorders, this edifying reference offers scientific background on normal ocular surface and tear film functioning; descriptions of the mechanisms involved in inflammation; and a...

The definitive text on the state-of-the-art in pediatric trauma care, this reference offers detailed descriptions of procedures in system design, pediatric resuscitation, supportive care, diagnostic imaging, pain management, and transfusion therapy by experts with hands-on experience in the field. Providing evidence-based recommendations, as...

Stressing major themes in the history of medicine, this Second Edition stimulates further exploration of the events, methodologies, and theories that shaped medical practices in decades past and in modern clinical practice-highlighting the practices of civilizations around the world, as well as the research of pioneering scientists and...

Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control,...

Based on extensive clinical, histological, and experimental studies, this guide serves as an authoritative source of information on the epidemiology, etiology, pathogenesis, diagnosis, and treatment of cutaneous lymphomas-reflecting the state-of-the-art in the field of cutaneous lymphomas-presented in the context of the brand-new...

Filling a gap in the literature, this reference provides concise and practical guidelines for the diagnosis and management of sinusitis and furnishes an authoritative outline of our current understanding of the pathophysiology of this condition. Addressing a wide spectrum of issues related to the identification, epidemiology, and etiology of...

Compiled by internationally recognized experts in trauma critical care,this sourcediscusses the entire gamut of critical care management of the trauma patient and covers several common complications and conditions treated in surgical intensive care units that are not specifically related to trauma.  Utilizing evidence-based guidelines...