Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and...

Progress in Inorganic Chemistry continues in its tradition of being the most respected forum for exchanging innovative research. This series provides inorganic chemists and materials scientists with a community where critical, authoritative evaluations of advances in every area of the discipline are exchanged. With contributions from...

This reference provides real-world examples, strategies, and templates for the implementation of effective design control programs that meet current ISO 9000 and FDA QSR standards and regulations-offering product development models for the production of safe, durable, and cost-efficient medical devices and systems.

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Providing a comprehensive survey of the clinical, educational, developmental, psychosocial, and transitional issues relevant to people with Down syndrome, this book addresses the needs of family members, caregivers, and professionals alike. Edited in association with the National Down Syndrome Society, this up-to-date treatment incorporates...

Handbook of Cardiac Electrophysiology provides a comprehensive introductory-level guide to invasive cardiac EP studies. Its focus is to enable the reader to understand and interpret the recording and stimulation techniques used during an EP study. The primary emphasis is on tachyarrhythmia diagnosis, but the book also includes bradycardias,...

Social and medical developments have recently led to a dramatic increase in life expectancy. This has inspired the study of organismic changes associated with healthy ageing, in particular the erosion of homeostatic capabilities in multiple endocrine systems.
This book reviews advances in the understanding of endocrine facets of...

This pioneering book explores in depth the role of neurotransmitters in conscious awareness. The central aim is to identify common neural denominators of conscious awareness, informed by the neurochemistry of natural, drug induced and pathological states of consciousness. Chemicals such as acetylcholine and dopamine, which bridge the synaptic...