Leland H. Hartwell Director, Fred Hutchinson Cancer Research Center, Nobel Laureate for Medicine, 2001 Yeast has proved to be the most useful single-celled organism for studying the fundamental aspects of cell biology. Resources are now available for yeast that greatly simplify and empower new investigations, like the presence of strains with...

Data mining and data modeling are hot topics and are under fast development. Because of its wide applications and rich research contents, a lot of practitioners and academics are attracted to work on these areas. In the view of promoting the communications and collaborations among the practitioners and researchers in Hong Kong, a two-day...

Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an...

This fully updated and dramatically expanded edition will allow family physicians and specialists to fully understand not only what they need to do, but also why. New to this edition-over half the book-are discussions of the clinical guidelines for selecting patients for densitometry measurements, various questionnaires and indices that have...

For more than a decade, Textbook of Physical Diagnosis has detailed how to derive the maximum diagnostic information from interviewing and examining patients. Now the text that has been labeled "the Gray's Anatomy of physical diagnosis" returns in a New Edition that continues to emphasize a "patient first" philosophy....

This book gives a comprehensive account of the practical aspects of Real time PCR and its application to veterinary diagnostic laboratories. The optimisation of assays to help diagnose livestock diseases is stressed and exemplified through assembling standard operating procedures from many laboratory sources. Theoretical aspects of PCR are dealt...

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly...