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Immune Checkpoint Blockade: Methods and Protocols (Methods in Molecular Biology)

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This detailed volume describes a series of techniques that are essential for evaluating the efficacy of new checkpoint blockade therapies as well as understanding the mechanisms behind the therapies that have already been approved. Beginning with a section on describing the tumor microenvironment and evaluating the immune system at a systemic level, the book continues by covering functional assays that provide answers to questions that may be raised after studying the immune system and its responses to immunotherapies, as well as the use of animal models in this research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Immune Checkpoint Blockade: Methods and Protocols serves to aid researchers in furthering our understanding of checkpoint blockage as well as the study of tumor immunology and the development of new immunotherapies.
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Regenerative and Cell Therapy: Clinical Advances (Ernst Schering Foundation Symposium Proceedings)
Regenerative and Cell Therapy: Clinical Advances (Ernst Schering Foundation Symposium Proceedings)

This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur...

Thieme Clinical Companions: Ultrasound
Thieme Clinical Companions: Ultrasound
Everything you need to know, see, and interpret in your daily work, presented in words and pictures!

Basic physical and technical principles, examination techniques, and documentation are covered in the gray part of the book.

What differential diagnoses should you consider for specific signs and symptoms? When can...

Medical Response to Terrorism: Preparedness and Clinical Practice
Medical Response to Terrorism: Preparedness and Clinical Practice
Even two decades ago, few would have imagined that terrorism would be planned and carried out on such an enormous scale as it is today. Terrorist attacks rely on horror and surprise, invoking different times, places, victims, and methods. Their purpose is to cause widespread confusion, fear, injury, and death. They disrupt security,...

Mac OS X: The Missing Manual, Second Edition
Mac OS X: The Missing Manual, Second Edition
New York Times computer columnist David Pogue has just updated his bestselling Mac OS X:The Missing Manual! And once again, he applies his scrupulous objectivity to this exciting new operating system, revealing which new features work well and which do not. With new material on almost every page, this second edition offers a wealth of...
Ajax: The Definitive Guide
Ajax: The Definitive Guide
Is Ajax a new technology, or the same old stuff web developers have been using for years? Both, actually. This book demonstrates not only how tried-and-true web standards make Ajax possible, but how these older technologies allow you to give sites a decidedly modern Web 2.0 feel. Ajax: The Definitive Guide explains how to use standards like...
Applications and Challenges of Geospatial Technology: Potential and Future Trends
Applications and Challenges of Geospatial Technology: Potential and Future Trends
This book advances the scientific understanding and application of space-based technologies to address a variety of areas related to sustainable development; including environmental systems analysis, environmental management, clean processes, green chemistry, and green engineering. Geo-spatial techniques have gained considerable interest in...
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