This substantially revised second edition contains new chapters on the role of GPIIb/IIIa blockade during acute coronary syndromes or with fibrinolytic therapy during acute myocardial infarctions, and updated and expanded information on the latest trials of GP IIb/IIIa inhibition during percutaneous coronary intervention. Additional...
Over 64,000 people in the US are living in limbo, awaiting an organ transplant.The good news about organ transplants is that they are becoming fairly routine surgical procedures. The even better news is that they do work miracles. People who have been in ill health for years often describe a feeling of being reborn after a...
Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and...
This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins. This field will...
The most authoritative and comprehensive guide on RLS to date, this expertly written source examines the pathogenesis, diagnosis, and treatment of a condition affecting nearly 10% of the population. Ranging from basic science to therapeutics, Restless Legs Syndrome analyzes the many new and emerging medications impacting the management of...
In a state-of-the-art synthesis of basic science and clinical practice, Roy Smith and a distinguished panel of researchers and clinicians review GH regulation and its action at the molecular level, and describe the basis for GH deficiency and the use of GH as therapy in a variety of clinical situations. The clinical presentation moves beyond...
A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity,Volume 2: In Vivo Models, Imaging, and Molecular Regulators contains cutting-edge protocols for classifying tumors...
Disease is often accompanied by pain. This book describes the techniques elaborated by interventional radiologists in the treatment and palliation of a variety of benign and malignant painful conditions. Each chapter concentrates on a particular aspect of pain management, with emphasis on practical issues. This book will serve as an...
Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new...
Somatostatin is a peptide isolated originally from the hypothalamus and considered as an inhibitor of growth hormone secretion. However, further studies have shown that the peptide was ubiquitously distributed and exerts a large spectrum of physiological effects, mostly of an inhibitory nature. The very short half-life of the native peptide...
The costs associated with a drug’s clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans.
Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of...
Proceedings of the FEMS Symposium on Genes and Proteins Underlying Microbial Urinary Tract Virulence: Basic Aspects and Applications, held September 16-19, 1999, in Pécs, Hungary.
Urinary tract infections are among the most frequent diseases caused by microbial pathogens. In this volume, researchers, clinical microbiologists...
