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Chirality in Drug Research (Methods and Principles in Medicinal Chemistry)

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Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals.

The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data.

In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions.

With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.

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Malliavin Calculus for Lévy Processes with Applications to Finance (Universitext)
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Here’s the book you need to prepare for Exam 70-219, Designing a Microsoft Windows 2000 Directory Services Infrastructure:

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Advanced Penetration Testing for Highly-Secured Environments: The Ultimate Security Guide
Advanced Penetration Testing for Highly-Secured Environments: The Ultimate Security Guide
Penetration testers are faced with a combination of firewalls, intrusion detection systems, host-based protection, hardened systems, and teams of knowledgeable analysts that pour over data collected by their security information management systems. In an environment such as this, simply running automated tools will typically...
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A Practical Guide to Trusted Computing
Use Trusted Computing to Make PCs Safer, More Secure, and More Reliable

 

Every year, computer security threats become more severe. Software alone can no longer adequately defend against them: what’s needed is secure hardware. The Trusted Platform Module (TPM) makes...

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