Computational techniques based on simulation have now become an essential part of the statistician's toolbox. It is thus crucial to provide statisticians with a practical understanding of those methods, and there is no better way to develop intuition and skills for simulation than to use simulation to solve statistical problems. Introducing...

Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB...

Intelligent Freeway Transportation Systems: Functional Design focuses on the efficient use of resources in the design of ITS. It discusses the principles of top down design starting with objectives and requirements, and provides guidance for the development and evaluation of functional design alternatives according to...