The present volume contains the papers accepted for presentation at the 6th International Workshop on Internet and Network Economics (WINE), an interdisciplinary forum devoted to the analysis of algorithmic and economic problems arising in the context of the Internet and the World Wide Web.

WINE 2010 was held December 13–17 in Stanford University. It was colocated with the 7th Workshop on Algorithms and Models for the Web Graph (WAW 2010).

In response to call for papers, the Program Committee received 95 submissions. The committee conducted a thorough evaluation and electronic discussion and eventually selected 52 papers (33 regular and 19 short papers) for inclusion in the proceedings.

This volume contains all the accepted papers. The workshop program also includes six distinguished lectures of Daron Acemoglu (Massachusetts Institute of Technology), Jennifer Chayes (Microsoft Research), Michael Kearns (University of Pennsylvania), Jon Kleinberg (Cornell University), Nimrod Megiddo (IBM Research), and Rakesh Vohra (Northwestern University).

We wish to thank the creators of EasyChair, a free conference management system, which significantly assisted the work of the Program Committee. We would also like to thank Google, Microsoft Research, and Yahoo! Research for supporting WINE. Finally, we wish to thank Stanford University, especially the staff of Stanford Computer Forum and the department of Management Science and Engineering.