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A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens. |
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Bioconjugation Protocols: Strategies and Methods (Methods in Molecular Biology)
Expert laboratorians update the classic bioconjugation methods and introduce valuable new techniques that go beyond pure biomedical applications to include elements from advanced organic synthesis, molecular biology, and materials science. These readily reproducible methods cover the preparation of protein conjugates using covalent and... | | Hands-On Sencha Touch 2: A Real-World App Approach
Get hands-on experience building speedy mobile web apps with Sencha Touch 2.3, the user interface JavaScript framework built specifically for the mobile Web. With this book, you’ll learn how to build a complete touch application, called Find a Cab, that has the look and feel of a native app on Android, iOS, Windows, and... | | Field Guide to Bedside Diagnosis (Field Guide Series)Field Guide to Bedside Diagnosis, Second Edition enables students and physicians to navigate from the patient's symptoms and presenting signs to the diagnosis. The book covers 139 chief complaints and signs and is organized to parallel the diagnostic reasoning process: a differential overview of probable causes, a diagnostic approach for each... |
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