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Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics (Ophthalmology Research)

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Angiogenesis is of fundamental importance in development, health, and disease. The study of angiogenesis in the eye, in particular, has increased exponentially in the last decade because retinal and choroidal neovascularization play an important role in the major blinding diseases of the industrialized world and represent an unprecedented economic burden on healthcare. It has now become an increasing challenge to manage the overwhelming bulk of information generated in the area of ocular angiogenesis. To meet the challenge, Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics assimilates the recent developments and summarizes the progress made in this field to date so that this information can be disseminated efficiently to the growing group of interested investigators, clinicians, and biotechnologists. Our intent is to foster new ideas, encourage discussion of the challenging concepts presented in the volume, increase our understanding of mechanisms that control this dynamic process, and translate the available information into targeted therapy.

Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.

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