Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that...

It happens everywhere?offices, schools, even your own backyard. Plus, seemingly anything can trigger it?cell phones, sirens, bad music, constant distractions, your boss, or even your spouse. We all know certain things get...

This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. Focused on the most highly representative genes that underlie the most common cancers, the book is aimed at advanced undergraduates who have completed introductory courses in genetics,...

The Basics of Digital Forensics provides a foundation for people new to the field of digital forensics. This book teaches you how to conduct examinations by explaining what digital forensics is, the methodologies used, key technical concepts and the tools needed to perform examinations. Details on digital forensics for computers,...

S. C. Sinha and S.R. Sprang:...

One of the most fruitful areas of research, as judged by the very large numbers of new cancer genes identified, has been the molecular analysis of recurrent chromosomal translocations. The original concept that gave rise to this book was that key scientists involved in the original isolation of the genes involved in each recurrent solid tumor...

Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory...

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. Neuregulin signals are also involved in the development diseases including breast cancer, heart disease and the pathogenesis of schizophrenia. This book reviews the biology of Neuregulins and their receptors and...