This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to...
Explore functional programming and discover new ways of thinking about code. You know you need to master functional programming, but learning one functional language is only the start. In this book, through articles drawn from PragPub magazine and articles written specifically for this book, you'll explore functional...
This book contains the papers presented during the 3rd International Workshop on Text Mining and its Applications held in Athens, Greece. This workshop is the final event of the activities of a network of excellence in the area of text mining and its applications. Knowledge Mining includes contributions in the areas of: Document processing,...
Semantics, Web services, and Web processes promise better re-use, universal interoperability and integration. Semantics has been recognized as the primary tool to address the challenges of a broad spectrum of heterogeneity and for improving automation through machine understandable descriptions.
Pattern Recognition has a long history of applications to data analysis in business, military and social economic activities. While the aim of pattern recognition is to discover the pattern of a data set, the size of the data set is closely related to the methodology one adopts for analysis. Intelligent Data Analysis: Developing New Methodologies...
Education and research in the field of database technology can prove problematic without the proper resources and tools on the most relevant issues, trends, and advancements.
Selected Readings on Database Technologies and Applications supplements course instruction and student research with quality chapters focused on key...
My great-grandfather was a furniture maker. I am writing this on his table, sitting in his
chair. His world was one of craft, “the skilled practice of a practical occupation.”1 He made
furniture late in life that was in superficial respects the same as that which he made earlier,
but one can see his craft advance.
...
Presents the most innovative results in carbene chemistry, setting the foundation for new discoveries and applications
The discovery of stable carbenes has reinvigorated carbene chemistry research, with investigators seeking to develop carbenes into new useful catalysts and ligands. Presenting the most innovative and...
The rapid growth of the Web in the past two decades has made it the largest
publicly accessible data source in the world. Web mining aims to discover
useful information or knowledge from Web hyperlinks, page contents,
and usage logs. Based on the primary kinds of data used in the
mining process, Web mining tasks can be categorized...
In 2005, Dharam Ahluwalia and Daniel Grumiller reported an unexpected theoretical discovery of mass dimension one fermions. These are an entirely new class of spin one half particles, and because of their mass dimensionality mismatch with the standard model fermions they are a first-principle dark matter candidate. Written by one of the...
A panel of leading academic and pharmaceutical investigators takes stock of the remarkable work that has been accomplished to date with proteasome inhibitors in cancer, and examines emerging therapeutic possibilities. The topics range from a discussion of the chemistry and cell biology of the proteasome and the rationale for proteasome...
This book explores the methionine dependence of cancer and its effects on aging, a great story of science that is not widely known. The chapters in this book describe the discovery of methionine dependence of cancer; the molecular basis for the increased methionine demand of cancer cells and tumors; the clinical application of...
