The practicing radiologist is continually challenged to update his/her competencies so
as to deliver state-of-the-art radiological care. Nowhere is this truer than in the rapidly
evolving world of magnetic resonance imaging, where innovations in both technology
and diagnostic pharmaceuticals have dramatically altered the landscape...
Over the past decades, paediatric oncologists, paediatric oncology nurses and
other health-care professionals caring for children with cancer have witnessed
profound changes in the nature of their practice. Whereas care of the child with
cancer was 30 or 35 years ago a matter of controlling pain and keeping the child
as...
With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial research. The book opens with the regulation of mitochondrial replication and biogenesis and reviews the mechanisms and functional consequences of...
This book was conceived one balmy March evening on the banks of the river Brisbane, in Queensland, Australia, where I had just arrived for a sabbatical, and it became clear that the traditions of measurement science and MRI should meet. The notion of a guide, a cook-book, for quantitative MRI (qMR) techniques took seed, and attained its own...
Malaria is still a major global health problem, killing more than one million
people every year. Almost all of these deaths are caused by Plasmodium
falciparum, one of the four species of malaria parasites infecting humans.
This high burden of mortality falls heavily on sub-Saharan Africa, where
over 90% of these deaths are...
Having first decided to organize and edit a book on heart failure in 1992 (with a 1994 publication date), we have been astounded at the changes in the field over a relatively brief 14-year period. It is with some amusement that we now look back at our first edition and note a combined chapter of beta agonists and...
A Personal History of Nuclear Medicine is an account of how nuclear medicine developed, and its basic philosophy in the past, present and future. The book outlines the history of the development of nuclear medicine as experienced by the author and describes the hurdles that nuclear medicine has had to face, in view of the perception of...
Critical care medicine is a cutting-edge medical field
that is highly evidence-based. Studies are continuously
published that alter the approach to patient care. As a critical
care clinician, I am aware of the tremendous commitment
required to provide optimal evidence-based care.
Pocket Guide to Critical Care...
The field of iminosugars is a very exciting area of research. These carbohydrate mimetics
were first imagined and synthesized by chemists in the 1960s before being isolated from
Nature a few years later. Since the discovery of their biological activity as potent glycosidase
inhibitors in the 1970s, iminosugars have been the subject...
It was with great pleasure that I accepted the invitation of Springer to edit
this book.My association with the vascular endothelium covers a large part of
my scientific career and, as with any good long-standing relationship, it has
had moments of great excitement and periods of laborious construction. It
has sometimes been...
Over the past three decades the field of immunotoxicology, the study of
the effects of exposure to drugs, chemicals, or physical/environmental agents
on the structure and function of the immune system has benefited from an
increasingly detailed understanding of the cellular and molecular basis of
innate and acquired immunity....
Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB...
