Blood Science is a relatively new discipline which merges biochemistry, haematology, immunology, transfusion science and genetics. This bringing together of traditional disciplines requires a corresponding change in education and training for healthcare scientists and Blood Science: Principles and Pathology is written in response to this...

There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol, sphingolipid, polyisoprenol and lipopeptide antigens. This volume provides a comprehensive discussion of these basic aspects of CD1 biology and summarizes the most recent research...

The book opens with chapters that focus on the development of molecular diagnostic tools and these are followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and...

In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system....

Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental...

This book highlights proteasome structures and how they are related to different aspects of proteasome function. Moreover, the book reports on the functional roles these highly developed proteolytic machines play within the cell. It was a great surprise to the scientific world that proteolysis provides crucial functions in cellular...

A review of our current understanding of Reoviridae entry, disassembly/assembly and egress in addition to updating high resolution structures of virus proteins and capsids from three different genera of the family. Most of our initial understanding of molecular biology and processes involved in virus replication and pathogenesis for the...

A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine’s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN...

The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The...