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Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volume 1
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volume 1
The aim of Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms is to present recent developments in cell survival and apoptotic pathways and their involvement in human diseases, such as cancers and neurodegenerative disorders. This requires an integration of knowledge from several fields of research, including...
Immunopharmacology of Platelets (Handbook of Immunopharmacology)
Immunopharmacology of Platelets (Handbook of Immunopharmacology)
Although anucleated, blood platelets are extraordinarily efficient cells and still the subject of fruitful investigations in haematology, in vascular physiology, in biochemistry, and more recently in immunology and in physiopathology where their metabolism has been implicated as a source of potential effector compounds. It...
Osteoimmunology: Interactions of the Immune and Skeletal Systems
Osteoimmunology: Interactions of the Immune and Skeletal Systems
It has been almost 40 years since it was fi rst observed that cells of the immune system could in fl uence the functions of bone [ 1 ] . Since that time, signi fi cant strides have been made in our understanding of the interactions between hematopoietic, immune, and bone cells. This fi eld is now known as...
Principles and Practice of Pediatric Surgery
Principles and Practice of Pediatric Surgery
In the preface to the text that preceded this edition, we predicted that the pace of change in the clinical practice of pediatric surgery, and in our understanding of the scientific principles that are the basis for that practice, would soon render the text obsolete. That expectation was more predictable than prescient,...
Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy (Current Topics in Microbiology and Immunology)
Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy (Current Topics in Microbiology and Immunology)

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models...

Hepatitis Delta Virus (Current Topics in Microbiology and Immunology)
Hepatitis Delta Virus (Current Topics in Microbiology and Immunology)

Hepatitis delta virus (HDV), which causes severe acute and chronic liver disease, was discovered nearly 30 years ago following the detection of a novel antigen-antibody system in hepatitis B virus carriers. HDV has continued to surprise and fascinate medical science ever since. This volume reviews recent developments in HDV research, from...

Office Andrology (Contemporary Endocrinology)
Office Andrology (Contemporary Endocrinology)

A comprehensive and practice-oriented resource guide to currently available diagnostic and treatment options for male infertility disorders. Topics covered range from basic sperm biology and male reproductive endocrinology, to immunology, specialized sperm testing, and the genetic background to male infertility. The authors emphasize the...

Advances in Multiple Sclerosis and Experimental Demyelinating Diseases (Current Topics in Microbiology and Immunology)
Advances in Multiple Sclerosis and Experimental Demyelinating Diseases (Current Topics in Microbiology and Immunology)
The past decade has witnessed significant advances in the understanding of the pathophysiology of MS and in the development of novel disease-modifying agents (DMA). The use of DMA in the treatment of patients with MS has drastically increased not only in the United States but throughout the rest of the world.

...
Toll-like Receptors: Roles in Infection and Neuropathology (Current Topics in Microbiology and Immunology)
Toll-like Receptors: Roles in Infection and Neuropathology (Current Topics in Microbiology and Immunology)

Mammalian Toll-like receptors (TLRs) were first identified in 1997 based on their homology with Drosophila Toll, which mediates innate immunity in the fly. In recent years, the number of studies describing TLR expression and function in the nervous system has been increasing steadily and expanding beyond their traditional roles in infectious...

Viruses and Nanotechnology (Current Topics in Microbiology and Immunology)
Viruses and Nanotechnology (Current Topics in Microbiology and Immunology)
Viral nanoparticles (VNPs) serve as excellent nanobuilding blocks for materials design and fabrication. The main advantages are their nanometer-range size, the propensity to self-assemble into monodisperse nanoparticles of discrete shape and size, the high degree of symmetry and polyvalency, the relative ease of producing large quantities, the...
Advanced Methods in Cellular Immunology
Advanced Methods in Cellular Immunology

Immunologists as well investigators in other disciplines may often use protocols involving the isolation, cultures and characterization of different types of leukocytes. Advanced Methods in Cellular Immunology is a collection of techniques in an easy-to-use format.

Each chapter provides readers with related program information, a...

The Complement System: Novel Roles in Health and Disease
The Complement System: Novel Roles in Health and Disease

As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost...

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