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Data Mining in Drug Discovery
Data Mining in Drug Discovery

Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different...

How Personal & Internet Security Works (How It Works)
How Personal & Internet Security Works (How It Works)

In 2003, fraud and identity theft cost consumers at least $437 million dollars. In 2004, the U.S. Federal Trade Commission received 247,000 consumer complaints in 2004 (up 15% from 2003), from individuals whose identity was stolen, and according to Reuters.com (2/2005), Americans lost $548 million dollars to identity theft...

Research and Trends in Data Mining Technologies and Applications
Research and Trends in Data Mining Technologies and Applications
In enterprises, a large volume of data has been collected and stored in data warehouses. Advances in data gathering, storage, and distribution have created a need for integrating data warehousing and data mining techniques. Mining data warehouses raises unique issues and requires special attention. Data warehousing and data mining are...
Robust Data Mining (SpringerBriefs in Optimization)
Robust Data Mining (SpringerBriefs in Optimization)

Data uncertainty is a concept closely related with most real life applications that involve data collection and interpretation. Examples can be found in data acquired with biomedical instruments or other experimental techniques. Integration of robust optimization in the existing data mining techniques aim to create new algorithms resilient to...

High-Throughput Screening in Drug Discovery, Volume 35
High-Throughput Screening in Drug Discovery, Volume 35

Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical...

Analysis of Biological Networks (Wiley Series in Bioinformatics)
Analysis of Biological Networks (Wiley Series in Bioinformatics)
An introduction to biological networks and methods for their analysis

Analysis of Biological Networks is the first book of its kind to provide readers with a comprehensive introduction to the structural analysis of biological networks at the interface of biology and computer science. The book begins with a brief overview of biological networks...

The Semantic Web - ISWC 2004: Third International Semantic Web Conference, Hiroshima, Japan, November 7-11, 2004. Proceedings
The Semantic Web - ISWC 2004: Third International Semantic Web Conference, Hiroshima, Japan, November 7-11, 2004. Proceedings
This book constitutes the refereed proceedings of the Third International Semantic Web Conference, ISWC 2004, held in Hiroshima, Japan in November 2004.

The 55 revised full papers presented together with abstracts of 2 invited talks were carefully reviewed and selected from a total of 227 submitted papers. The papers are organized in topical...

Nonnegative Matrix and Tensor Factorizations: Applications to Exploratory Multi-way Data Analysis and Blind Source Separation
Nonnegative Matrix and Tensor Factorizations: Applications to Exploratory Multi-way Data Analysis and Blind Source Separation
This book provides a broad survey of models and efficient algorithms for Nonnegative Matrix Factorization (NMF). This includes NMF’s various extensions and modifications, especially Nonnegative Tensor Factorizations (NTF) and Nonnegative Tucker Decompositions (NTD). NMF/NTF and their extensions are increasingly used as tools in signal and...
Applied Data Mining
Applied Data Mining

Data mining has witnessed substantial advances in recent decades. New research questions and practical challenges have arisen from emerging areas and applications within the various fields closely related to human daily life, e.g. social media and social networking. This book aims to bridge the gap between traditional data mining and...

Data Mining for Systems Biology: Methods and Protocols (Methods in Molecular Biology)
Data Mining for Systems Biology: Methods and Protocols (Methods in Molecular Biology)

The post-genomic revolution is witnessing the generation of petabytes of data annually, with deep implications ranging across evolutionary theory, developmental biology, agriculture, and disease processes. Data Mining for Systems Biology: Methods and Protocols, surveys and demonstrates the science and technology of converting...

Rough Computing: Theories, Technologies and Applications
Rough Computing: Theories, Technologies and Applications
Rough set theory is a new soft computing tool which deals with vagueness and uncertainty. It has attracted the attention of researchers and practitioners worldwide, and has been successfully applied to many fields such as knowledge discovery, decision support, pattern recognition, and machine learning.

Rough Computing: Theories,...

Clustering for Data Mining: A Data Recovery Approach (Chapman & Hall/CRC Computer Science & Data Analysis)
Clustering for Data Mining: A Data Recovery Approach (Chapman & Hall/CRC Computer Science & Data Analysis)
Often considered more as an art than a science, the field of clustering has been dominated by learning through examples and by techniques chosen almost through trial-and-error. Even the most popular clustering methods--K-Means for partitioning the data set and Ward's method for hierarchical clustering--have lacked the theoretical...
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