This practical reference examines the advantages and disadvantages of polypharmacy in psychiatry, and provides up-to-date clinical guidelines on the appropriate use of combinations of pharmacological therapy in major psychiatric disorders-including multidisciplinary approaches to treatment, such as social work and psychopharmacology, and an...
One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells...
This book is a collection of representative and novel works done in Data Mining, Knowledge Discovery, Clustering and Classification that were originally presented in French at the EGC'2012 Conference held in Bordeaux, France, on January 2012. This conference was the 12th edition of this event, which takes place each year and which is now...
âThe last decades have seen remarkable advances in computerâaided design, engineering and manufacturing technologies, multiâvariable simulation tools, medical imaging, biomimetic design, rapid prototyping, micro and nanomanufacturing methods and information management resources, all of which provide new horizons for the...
The geography of networks and R&D collaborations, in particular the spatial dimension of interactions between organisations performing joint R&D, have attracted a burst of attention in the last decade, both in the scientific study of the networks and in the policy sector. The volume is intended to bring together a selection of...
Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal...
Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to...
This book covers various aspects of lasers in materials science, including a comprehensive overview on basic principles of laser-materials interactions and applications enabled by pulsed laser systems. The material is organized in a coherent way, providing the reader with a harmonic architecture.
While systematically covering the...
This volume contains the proceedings from two closely related workshops: Computational Diffusion MRI (CDMRI’13) and Mathematical Methods from Brain Connectivity (MMBC’13), held under the auspices of the 16th International Conference on Medical Image Computing and Computer Assisted Intervention, which took place in Nagoya, Japan,...
This thesis explores ultracold quantum gases of bosonic and fermionic atoms in optical lattices. The highly controllable experimental setting discussed in this work, has opened the door to new insights into static and dynamical properties of ultracold quantum matter. One of the highlights reported here is the development and application of a...
An expert review of recent progress in the study of turbulent flows with a focus on recently identified organized structures.
This book reviews the recent progress in the study of the turbulent flows that sculpt the Earth’s surface, focusing in particular on the organized structures that have been...
The overwhelming data produced everyday and the increasing performance and cost requirements of applications are transversal to a wide range of activities in society, from science to industry. In particular, the magnitude and complexity of the tasks that Machine Learning (ML) algorithms have to solve are driving the need to devise...
