Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. The first reference devoted to the topic, this up-to-date resource covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the...

The cytological diagnosis of soft tissue tumours, based on fine needle aspirates, has been debated and at times dis couraged except in the diagnosis of lipoma. Soft tissue tumours are relatively rare in spite of the fact that more than 100 benign subtypes, over 50 variants of sarcoma and a number of 'border-line' entities have been...

This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools...

The book aims at presenting technical and financial features of life insurance, non-life insurance, pension plans. The book has been planned assuming non-actuarial readers as its "natural" target, namely - advanced undergraduate and graduate students in Economics, Business and Finance; - professionals and technicians operating in...

Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes...

This book is for big...