M. Gabriel Khan, MD, concisely assembles in a reader friendly format all the clinically useful information that an internist needs in both his daily rounds and abusy office practice to find correct clinical diagnoses and choose optimal pharmacologic therapies for their patients. Highlights include a simplified method for recognition of, and a...

Leading pain specialist Dawn A. Marcus, MD, offers primary care clinicians practical, clear, and succinct evidence-based approaches to the diagnosis and treatment of the painful conditions they see in their offices every day. The author simplifies the often complex care of patients with chronic pain by providing practical strategies for...

This is a newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics. William B. White, MD, and a panel of highly experienced clinicians critically review every aspect of out-of-office evaluation of blood pressure. The world-class opinion leaders writing here describe the significant advances in our...

A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the...

This 2nd revised edition covers management and treatment of bladder and bowel dysfunctions in men and women, pelvic organ prolapse, issues concerning the elderly, neurologically impaired patients and those with pelvic pain. New chapters cover quality of life, treatment of bladder and bowel dysfunction in children, the history of pelvic floor...

It is well-known that the daily diet plays an important role in the preservation and integrity of renal function in patients with chronic kidney disease. However, there currently exists some confusion as to the right diet because of the MDRD (Modification of Diet in Renal Disease) study, which has shown that a low-protein diet does not have a...

This book unfolds the history of the discovery of the transmembrane channel which is responsible for the ‘funny’ or I_f current, the primary modulator of heart rate. Inhibition of this current leads to slowing of the heart rate, which is an important component of the successful management of angina pectoris....

Over the next decade, the global number of people with diabetes and at risk of diabetes and cardiovascular disease is expected to grow by 25%, largely driven by the rising prevalence of obesity and inactivity. The problem is especially serious in Asia, where the WHO predicts that in less than a decade, 60% of the worldwide population with...

A quick reference guide to the diagnosis and treatment of common primary care problems. The information is presented in such a way as to help students and physicians quickly form a list of possible diagnoses, perform a cost-effective diagnostic work-up, and prescribe therapy for the most common causes of acute and chronic complaints....

This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance...