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Calcium Signalling in Cancer
Calcium Signalling in Cancer

Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an...

From Melanocytes to Melanoma: The Progression to Malignancy
From Melanocytes to Melanoma: The Progression to Malignancy

Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They...

Lymphoma (Methods in Molecular Medicine)
Lymphoma (Methods in Molecular Medicine)

A cutting-edge collection of readily reproducible molecular techniques to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and...

The Technical and Social History of Software Engineering
The Technical and Social History of Software Engineering

“Capers Jones has accumulated the most comprehensive data on every aspect of software engineering, and has performed the most scientific analysis on this data. Now, Capers performs yet another invaluable service to our industry, by documenting, for the first time, its long and fascinating history....

Indra's Net and the Midas Touch: Living Sustainably in a Connected World
Indra's Net and the Midas Touch: Living Sustainably in a Connected World

We live today in a global web of interdependence, connected technologically, economically, politically, and socially. As a result of these expanding and deepening interdependencies, it has become impossible fully to control -- or foretell -- the effects of our actions. The world is rife with unintended consequences. The first law of human...

Digital Da Vinci: Computers in the Arts and Sciences
Digital Da Vinci: Computers in the Arts and Sciences

“Science is art,” said Regina Dugan, senior executive at Google and former director of DARPA. “It is the process of creating something that never exists before. ... It makes us ask new questions about ourselves, others; about ethics, the future.” This second volume of the Digital Da Vinci book series leads the...

Oceans in Decline
Oceans in Decline

What is happening in our oceans? By describing their main elements, this book shows how and why the oceans are being transformed, and suggests possible future scenarios to address this complex, yet often-asked, question. The ocean is being dramatically transformed, but the magnitude of this transformation remains unclear since the...

Stewarding Sustainability Transformations: An Emerging Theory and Practice of SDG Implementation
Stewarding Sustainability Transformations: An Emerging Theory and Practice of SDG Implementation
In the context of the world’s pressing sustainability challenges this new Report to the Club of Rome presents a novel approach to navigating collaborative change in partnerships between governments, research institutions, corporations and civil society activists. With reference to the 17 Sustainable Development Goals and the Planetary...
States, Intergovernmental Relations, and Market Development: Comparing Capitalist Growth in Contemporary China and 19th Century United States (Governing China in the 21st Century)
States, Intergovernmental Relations, and Market Development: Comparing Capitalist Growth in Contemporary China and 19th Century United States (Governing China in the 21st Century)
This book is a theoretical and empirical analysis of institutional foundation of long-term economic growth from the perspective of state-market and central-local relations. The book argues that, in order to safeguard sustainable market development, it is necessary to centralize certain functions of the state to overcome local predatory...
The 100X Leader: How to Become Someone Worth Following
The 100X Leader: How to Become Someone Worth Following

Become the leader others want to follow

Forget everything you know about motivating others and building a harmonious workplace. If you want to get the best out of people, you must be willing to fight. But, that doesn't mean you become a dominator, nor does coddling others work.

The best leader...

The Inside Track to Excelling As a Business Analyst: Soft Skills That Can Accelerate Your Career
The Inside Track to Excelling As a Business Analyst: Soft Skills That Can Accelerate Your Career

The role of the business analyst sits at the intersection of business operations, technology, and change management. The job requires a plethora of both soft skills and technical skills, as it must translate the needs of business users into action items for functional applications. On top of this, in-demand technologies...

Modern Soil Microbiology, Third Edition
Modern Soil Microbiology, Third Edition

The living soil is crucial to photosynthesis, biogeochemical cycles, global food production, climate change, biodiversity, and plant and animal health. In the past decade, scientists have made significant advances in soil microbiology research. While the basic principles are now better understood, knowledge has been forthcoming on...

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