The tumor necrosis factor/receptor [TNF/TNFR] superfamily consists of more than 20 transmembrane proteins with conserved N-terminal cysteine-rich domains [CRDs] in the extracellular ligand binding region. Members have wide tissue distribution and play important roles in biological processes such as lymphoid and neuronal development, innate...
The field of peptide based cancer vaccines has evolved tremendously in the last decade of this century. The exploration on how to apply the peptide knowledge for vaccination purposes began when it was demonstrated that these peptides after being mixed into adjuvants actually induced T cell responses that could prevent virus infections and...
The catecholamine dopamine (DA) plays a key role in the physiology of most vertebrate and invertebrate organisms. In addition to its role as a transmitter in the nervous system, it has a role in development. The relatively few DA neurons in the mammalian brain have important roles in many neural functions including fine motor integration,...
Ethnic specificity has become an integral part of research in the overlapping sciences of pharmacogenetics and pharmacogenomics. Pharmacogenomics in Admixed Populations was conceived to compile pharmacogenetic/-genomic (PGx) data from peoples of four continents: Africa, America, Asia and Oceania, where admixture and population stratification...
Clusterin is a multifunctional protein which was independently discovered by more than ten different research groups in the 1980s. New roles of clusterin in brain functions have come to llight which are summarized here by the researchers involved. Recent discoveries include a unique lipoprotein particle containing clusterin and apoE secreted...
App Development Recipes for iOS and watchOS explores the technical side of app development with tips and tricks to avoid those little things that become big frustrations, outside of the realm of development, causing many people to throw up their hands and say “It’s just not worth the...
When looking for ways to improve your website, how do you decide which changes to make? And which changes to keep? This concise book shows you how to use Multiarmed Bandit algorithms to measure the real-world value of any modifications you make to your site. Author John Myles White shows you how this powerful class of algorithms can...
