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Bioinformatics - From Genomes to Therapies

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"This treatise on bioinformatics is an excellent reference set to use as additional reading in advanced undergraduate and graduate courses..."
(ChemMedChem, October 2007)

Once again, Thomas Lengauer has succeeded in creating a comprehensive and immensely useful resource that meets even the high standards of professionals in the pharmaceutical and medical sector.

By extending the classical application areas of bioinformatics to the latest approaches in analyzing molecular networks and predicting molecular function, this handbook serves as a one-stop resource for every bioinformatics user in the life and medical sciences. With contributions by more than 80 of the world's leading bioinformaticians, it is unrivalled in terms of both scientific authority and accuracy. Its coverage extends beyond the biological background and methodological basics to include such topical aspects as the optimization of drug leads, personalization of drug therapies, and disease-specific applications, such as bacterial or viral infections, supported by numerous references to bioinformatics software and data resources throughout.

The best single information source available—written by professionals for professionals.

Thomas Lengauer is Director of the Max-Planck Institute for Informatics in Saarbrucken, Germany. He has been involved in computational biology research since the beginning of the 1990s, focusing on protein bioinformatics, computational drug screening and design, as well as bioinformatics for understanding and curing diseases. He is a founding member of the International Society for Computational Biology (ISCB), a member of the steering board of the international conference series RECOMB, and headed the steering board of the European bioinformatics conference series ECCB since its foundation in 2002 until 2005. In 2001 he co-founded BioSolveIT GmbH, which develops and distributes chemoinformatics software. A member of the German Academy of Sciences Leopoldina, in 2003 Professor Lengauer received the Konrad Zuse Medal of the German Informatics Society and the Karl Heinz Beckurts Award.

About the Author

Thomas Lengauer (born 1952) studied Mathematics and Informatics at Berlin and Stanford. After a brief stay at the Bell Laboratories, he held various academic positions at the universities of Saarbruecken, Paderborn, and Bonn. From 1992 to 2001, he headed the Institute for Algorithms and Scientific Computing at the GBM in Sankt Augustin (Germany). Since 2001, he is director at the Max-Planck-Institute for Informatics in Saarbruecken (Germany).
Professor Lengauer has recently been awarded the Konrad-Zuse-Medal, the highest honor of the German Informatics Society.

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