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Infectious agents have been recognized to involve the heart and vascular
system for well over a century. Traditional concepts and teachings of their
involvement in the pathogenesis of disease have been by a few established
mechanisms. Bacterial and occasionally fungal microorganisms were known
to invade and multiply on the endocardium of valves, vascular prostheses or
shunts and aneurysm. Similarly viral, bacterial, mycobacterial, fungal, and
parasitic pathogens could cause disease by invasion of the pericardium and
muscles of the heart. Pathogenesis of some diseases of the endocardium,
myocardium, and pericardium could involve indirect mechanisms with
molecular mimicry inducing injury through an autoimmune process, such as
in rheumatic heart disease and post viral cardiomyopathy.
It was recognized by the mid-20th century that Treponema pallidum, the
etiology of syphilis, could cause cardiovascular damage (aortitis and aortic
aneurysm) by obliteration of the vasa vasorum supplying the root of the aorta
by endarteritis obliterans, and by then the connection between streptococcal
infection and rheumatic heart disease was clear.
Infectious agents have been recognized to involve the heart and vascular system for well over a century. Traditional concepts and teachings of their involvement in the pathogenesis of disease have been by a few established mechanisms. Since the last decade of the 20th century there has been renewed interest in the medical and public media on infectious diseases affecting the cardiovascular and cerebrovascular systems, through their relationship with the development of acceleration of atherosclerosis. This volume highlights and reviews new perspectives of infections on the cardiovascular system as never before. It is a truly valuable resource for scientists, researchers, residents, and fellows in the fields of infectious disease, cardiology, and microbiology. |
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Shrimp: The Endless Quest for Pink Gold
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Completely updated every year (unlike most of the competition), Frommer's England 2011 features gorgeous color maps, a detachable foldout map of London, and details on all of the country's top cities, villages, gardens, countryside destinations, and more.
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Human Machine Interaction, or more commonly Human Computer Interaction, is the study of interaction between people and computers. It is an interdisciplinary field, connecting computer science with many other disciplines such as psychology, sociology and the arts.
The present volume documents the results of the MMI research program... |
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