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Profiles potential treatment approaches for cardiac arrhythmias
Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology.
Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections:
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Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs.
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Section Two addresses safety pharmacology, including the concept of "repolarization reserve," safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs.
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Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets.
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Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids).
Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike. |
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 Embedded Computer Systems: Architectures, Modeling, and Simulation: 8th International Workshop, SAMOS 2008, Samos, Greece, July 21-24, 2008, ProceedingsThis book constitutes the refereed proceedings of the 8th International Workshop on Systems, Architectures, Modeling, and Simulation, SAMOS 2008, held in Samos, Greece, in July 2008.
The 24 revised full papers presented together with a contamplative keynote and additional papers of two special workshop sessions were carefully reviewed and... |  |  Computer Graphics Through OpenGL®: From Theory to Experiments
COMPREHENSIVE COVERAGE OF SHADERS AND THE PROGRAMMABLE PIPELINE
From geometric primitives to animation to 3D modeling to lighting, shading and texturing, Computer Graphics Through OpenGL®: From Theory to Experiments is a comprehensive introduction to computer graphics which uses an active... |  |  Migrating to Android for iOS Developers
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