Hilbert space frames have long served as a valuable tool for signal and image processing due to their resilience to additive noise, quantization, and erasures, as well as their ability to capture valuable signal characteristics.  More recently, finite frame theory has grown into an important research topic in its own right, with a myriad...

Wallis's book on discrete mathematics is a resource for an introductory course in a subject fundamental to both mathematics and computer science, a course that is expected not only to cover certain specific topics but also to introduce students to important modes of thought specific to each discipline . . . Lower-division undergraduates...

This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target validation to their use in clinical development programs. Chapters are devoted to the description of the drug discovery process, to the various imaging modalities preclinically and clinically, to applications of...

Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which...

Revised and updated, this second edition of Walter Gautschi's successful Numerical Analysis explores computational methods for problems arising in the areas of classical analysis, approximation theory, and ordinary differential equations, among others. Topics included in the book are presented with a view toward...

2nd ed. includes new chapters on labeling and communications networks and small worlds, as well as expanded...

Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially...

This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future...

This topical volume provides an overview of clinically relevant data on anticancer agents. It is not only intended medical doctors working with cancer patients, and for medical researchers and students. The different classes of anticancer drugs are described by international authorities on the various topics. Apart from new targets for...

Despite tremendous advances in the understanding of the sensory nervous system which have accompanied the recent explosive growth of the neurosciences, rema- ably few innovative medicines directed towards pain and inflammation are ava- able. Indeed, many patients are still prescribed analgesic and anti-inflammatory medications that were...

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They...

Entry Inhibitors in HIV Therapy details the current status of this relatively new and very dynamic class of inhibitors. A unique overview of obstacles and accomplishments is presented. The impact of viral sequence diversity on this class of inhibitors is discussed, and a connection between basic research and clinical studies is shown. The...