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Comprehensive Textbook of Genitourinary Oncology
Comprehensive Textbook of Genitourinary Oncology

Thoroughly revised for its Third Edition, this volume is the most comprehensive, multidisciplinary text on genitourinary cancers. This edition has two new editors—Frans M.J. Debruyne and W. Marston Linehan—and more than 50% new contributors. Seventeen new chapters cover familial prostate cancer, biology of bone...

Targeted Therapies in Cancer: Myth or Reality? (Advances in Experimental Medicine and Biology)
Targeted Therapies in Cancer: Myth or Reality? (Advances in Experimental Medicine and Biology)
Cancers share a restricted set of characteristics crucial to the tumor phenotype: proliferation in the absence of external growth stimuli, avoidance of apoptosis and no limits to replication, escape from external growth-suppressive forces and the immune response, an inflammatory micro-environment with new blood vessel...
Nutrient-Gene Interactions in Cancer
Nutrient-Gene Interactions in Cancer

The complete mapping of the human genome, along with the development of sophisticated molecular technologies, has accelerated research on the relationship between nutrients and genes. This has led to compelling evidence garnered from epidemiological and experimental observations supporting the idea that the interaction between nutrients and...

COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)
COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)

The revelation that aspirin and aspirin-like compounds have notable antineoplastic properties has revolutionized cancer research. COX-2 Blockade in Cancer Prevention and Therapy chronicles the evidence and presents exciting new opportunities for the use of cyclooxygenase-2 (COX-2) blockade in the prevention and treatment of cancer. The text...

Information Theory and Statistical Learning
Information Theory and Statistical Learning
This book presents theoretical and practical results of information theoretic methods used in the context of statistical learning. Its major goal is to advocate and promote the importance and usefulness of information theoretic concepts for understanding and developing the sophisticated machine learning methods necessary not only...
Human Retroviral Infections: Immunological and Therapeutic Control
Human Retroviral Infections: Immunological and Therapeutic Control
The mechanisms of disease production by infectious agents are presently the focus of an unprecedented flowering of studies. The field has undoubtedly received impetus from the considerable advances recently made in the understanding of the structure, biochemistry, and biology of viruses, bacteria, fungi, and other parasites....
Diseases of the Liver & Biliary System
Diseases of the Liver & Biliary System
The eleventh edition welcomes the new Millenium. Progress in basic and clinical hepatology remains exponential. Since 1997, the advances have been wideranging, with those in molecular and cellular biology, and in diagnosis and treatment, leading the way. In a world in which information technology gives all too ready...
The Princeton Companion to Mathematics
The Princeton Companion to Mathematics

This is a one-of-a-kind reference for anyone with a serious interest in mathematics. Edited by Timothy Gowers, a recipient of the Fields Medal, it presents nearly two hundred entries, written especially for this book by some of the world's leading mathematicians, that introduce basic mathematical tools and vocabulary; trace the...

Essentials of Apoptosis: A Guide for Basic and Clinical Research
Essentials of Apoptosis: A Guide for Basic and Clinical Research
Life and death are topics that no one takes lightly. In the cell, death by apoptosis is just as fundamental as proliferation for the maintenance of normal tissue homeostasis. Too much or too little apoptosis can lead to developmental abnormality, degenerative diseases, or cancers. Although apoptosis, or programmed cell death (PCD),...
The Biology of Schwann Cells: Development, Differentiation and Immunomodulation
The Biology of Schwann Cells: Development, Differentiation and Immunomodulation
It is now over 200 years since Theodore Schwann first described the cell which bears his name. Such early descriptions of nervous system components were done without the powerful microscopes we have today, yet Schwann and Ramon Y. Cajal made foundation observations which still stand. Cajal’s papers, especially, show the...
Infertility in the Modern World: Present and Future Prospects (Biosocial Society Symposium Series)
Infertility in the Modern World: Present and Future Prospects (Biosocial Society Symposium Series)

As we enter the twenty-first century, a number of medical, environmental, and social changes have profoundly affected human reproduction. This book discusses some of the more dramatic changes in an accessible manner, illustrating the ways in which human biology and culture can affect fertility. It provides a unique interdisciplinary...

Iminosugars: From Synthesis to Therapeutic Applications
Iminosugars: From Synthesis to Therapeutic Applications
The field of iminosugars is a very exciting area of research. These carbohydrate mimetics were first imagined and synthesized by chemists in the 1960s before being isolated from Nature a few years later. Since the discovery of their biological activity as potent glycosidase inhibitors in the 1970s, iminosugars have been the subject...
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