A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include...

Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to...

Growing numbers of men and many more women are suffering from crippling bone loss called osteoporosis. By 2050 50% of Americans over 50 will be at risk of, or actually have, osteoporosis. In this book the reader will meet the newest real and possible bone builders and learn how they might work. These include novel steroids, an osteogenic...

Oxygen-ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classic biochemical, physiological and pharmacological...

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This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan,...

Physics in Biology and Medicine, Fourth Edition explores concepts in physics as they apply to living systems. The discussion is organized into 18 chapters encompassing thermodynamics, electricity, optics, sound, solid mechanics, fluid mechanics, and atomic and nuclear physics. Each chapter provides a brief review of the background physics...

"Lecture Notes: Obstetrics and Gynaecology" provides a concise introduction to obstetrics and gynaecology for medical students and junior doctors. Six sections examine the female development from the early years to old age. The text starts with a section on Basic Science. Self-assessment questions are found throughout the text to...

This gorgeous, full-color atlas and case-book presents more than sixty cases with over one hundred associated, super high-quality clinical images that a physician needs to be able to rapidly recognize and know for accurate, expedient diagnosis and treatment. The images are presented with the patient’s brief medical history, followed by...

MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor...

Since their first application in 1982, Totally Implantable Venous Access Devices (TIVADs) have become increasingly important in the clinical practice, as more intensive chemotherapy and parenteral treatments have come into use. At this time, there is objective evidence that TIVADs are a safe, effective strategy for long-term venous access;...