For a very few cancers, treatment options are minimally invasive, resoundingly curative, and have very few side effects. However, most cancer patients face treatment options that are less than ideal. The odds they have been given for a chance of recurrence might be frightening. Or, the "cure rate" of treatment might be...
This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology.
The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The...
This book builds a novel bridge from molecular research to clinical therapy. This approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes...
Featuring a focus on mechanisms, this popular reference comprehensively covers important concepts in physiology, both at the organ system and cellular levels. Easy to read and user-friendly, the revised third edition stresses essential and relevant content with absolute clarity and includes concise step-by-step explanations complemented by...
This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan,...
This volume deals with aspects of the cytoskeleton in different cell types and also describe examples of changes in the cytoskeleton which occur during various pathological states. These studies bring the exciting area of cytoskeleton research into the domain of medical science.
This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system.
Written by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the...
Research on bone remodeling has resulted in much new information and has led to improvements in design and biomedical practices. Mechanics of Cellular Bone Remodeling: Coupled Thermal, Electrical, and Mechanical Field Effects presents a unified exploration of recent advances, giving readers a sound understanding of...
Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various “omics” technologies and their...
This book reviews the state-of-the-art in fuel cells (low and high temperature) across all the types applied in the field today and assesses current trends in development. The main technology problems are discussed and current gaps to market success identified. The innovations covered in the book deliver new answers to pertinent problems...
The unexpected results from an investigation into hereditary congenital anorectal malformations of pig embryos have demonstrated the weakness of earlier interpretations and constructions and underlined the need for a new inquiry into the normal development of the area in human embryos. It demonstrated that although data from malformations may...