A comprehensive reference survey on the identification and development of promising cancer chemopreventive agents that will help stimulate further novel research and new approvable drugs. For each agent, the authors review the relevant mechanisms of action, the criteria for populations benefiting from intervention, the safety and...

Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transd- tion that directly contribute to a loss of this...

Focusing on specific pathways...

One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells...

HERBAL MEDICINE FROM A WESTERN POINT OF VIEW

Herbal remedies have become a major factor in American health care. Botanicals like Ginseng, Ma Huang, St. John's Wort, and Valerian are now household words throughout the world. Since many of these natural drugs are sold over the counter, often consumers mistakenly assume that...

Exploring the role of Immunoglobulin-E (IgE) in human disease, this reference summarizes current research on the mechanisms and utilization of anti-IgE therapeutics in the treatment of IgE-mediated allergic disease, inflammation, and asthma-discussing the structural composition of high- and low-affinity IgE receptors, the airway cells that...

Features a comprehensive summary of the chemical, physiological, and nutritional relationships of all recognized vitamins!

Maintaining the standards of excellence set forth in the previous editions, the Handbook of Vitamins, Third Edition presents a thorough examination of the fundamental characteristics, functions, and roles...

Thoroughly updated to reflect the CompTIA Network+ N10-006 exam, Networking Essentials, Fourth Edition is a practical, up-to-date, and hands-on guide to the basics of networking. Written from the viewpoint of a working network administrator, it requires absolutely no experience with either network concepts or...

"A great overview of the new threats created...

The thrilling memoir of the world's most wanted computer hacker

"Mitnick manages to make breaking computer code sound as action-packed as robbing a bank." -- NPR

Kevin Mitnick was the most elusive computer break-in artist in history. He accessed...