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Reactive oxygen species (ROS) are  increasingly appreciated as down-stream effectors of cellular damage and dysfunction under natural and anthropogenic stress scenarios in aquatic systems. This comprehensive volume describes oxidative stress phenomena in different climatic zones and groups of organisms, taking into account specific...

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for...

The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature...

This book covers everything you need to know to write professional-level cryptographic code. This expanded, improved second edition includes about 100 pages of additional material as well as numerous improvements to the original text. The chapter about random number generation has been completely rewritten, and the latest cryptographic...

Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying...

Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being triggered by different endogenous and exogenous factors. Since aging is a major risk factor in connection with a variety of human disorders, it is increasingly becoming a central topic in biochemical...

Volume IV continues the author's odyssey on l-D cellular automata as chronicled in Volumes I, II and III, by uncovering a novel quasi-ergodicity phenomenon involving orbits meandering among omega-limit orbits of complex (group 5) and hyper (group 6) Bernoulli rules. This discovery is embellished with analytical formulas characterizing the...

Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their...

Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is formed in an initial step of lipid peroxidation. Lipid hydroperoxide is also known as a potential source of singlet oxygen. Harmful aldehydes are formed when the lipid hydroperoxide is degraded....

It covers such diverse subjects as conservative computation in billiard ball models...