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Atlas of Confocal Laser Scanning In-vivo Microscopy in Ophthalmology
Atlas of Confocal Laser Scanning In-vivo Microscopy in Ophthalmology

Confocal microscopy with laser scanning technology yields in-vivo images of ocular and ocular adnexal surfaces that are so brilliant that they rival histology in terms of quality.This unique atlas and textbook demonstrates normal in-vivo anatomy of the cornea, limbus and conjunctiva, quantifies various cellular structures using cell-density...

Built to Last: Successful Habits of Visionary Companies
Built to Last: Successful Habits of Visionary Companies

"This is not a book about charismatic visionary leaders. It is not about visionary product concepts or visionary products or visionary market insights. Nor even is it about just having a corporate vision. This is a book about something far more important, enduring, and substantial. This is a book about visionary...

Targeted Therapies in Cancer: Myth or Reality? (Advances in Experimental Medicine and Biology)
Targeted Therapies in Cancer: Myth or Reality? (Advances in Experimental Medicine and Biology)
Cancers share a restricted set of characteristics crucial to the tumor phenotype: proliferation in the absence of external growth stimuli, avoidance of apoptosis and no limits to replication, escape from external growth-suppressive forces and the immune response, an inflammatory micro-environment with new blood vessel...
Cancer Drug Resistance (Cancer Drug Discovery and Development)
Cancer Drug Resistance (Cancer Drug Discovery and Development)

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport,...

Cisplatin: Chemistry and Biochemistry of a Leading Anticancer Drug
Cisplatin: Chemistry and Biochemistry of a Leading Anticancer Drug

30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics...

Endocannabinoids: The Brain and Body's Marijuana and Beyond
Endocannabinoids: The Brain and Body's Marijuana and Beyond

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana,  and the finding of endogenous cannabinoids, which...

Pancreatic Cancer: Methods and Protocols (Methods in Molecular Medicine)
Pancreatic Cancer: Methods and Protocols (Methods in Molecular Medicine)
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer death in the United States. Annually approximately 30,000 Americans are diagnosed with the disease and most will die from it within five years. Pancreatic ductal adenocarcinoma is unique because of its late onset in age, high mortality, small tumor samples...
Cancer Precursors: Epidemiology, Detection, and Prevention
Cancer Precursors: Epidemiology, Detection, and Prevention
Dramatic advances in our understanding of cancer causation have come from epidemiologic and laboratory research, particularly over the past two decades. These developments have included a broadening interest in the critical events that take place during the early stages of the dynamic multistep process leading to invasive...
Handbook of Cell-Penetrating Peptides, Second Edition (Pharmacology and Toxicology: Basic and Clinical Aspects)
Handbook of Cell-Penetrating Peptides, Second Edition (Pharmacology and Toxicology: Basic and Clinical Aspects)

Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field. The constant internal change in the field of cell-penetrating peptides (CPPs) is due to recent research uncovering apparent ambiguities in...

Hypertension Primer: The Essentials of High Blood Pressure
Hypertension Primer: The Essentials of High Blood Pressure
We are delighted to bring you the Hypertension Primer, Third Edition, a decade after the First Edition was launched. Given the breadth and depth of information available in the continuously expanding field of hypertension, our Primer remains a...
Multiscale Modeling of Developmental Systems, Volume 81 (Current Topics in Developmental Biology)
Multiscale Modeling of Developmental Systems, Volume 81 (Current Topics in Developmental Biology)

Mathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at the moment, beyond the theoretical techniques available. Developmental biology, due to its complexity, has lagged somewhat behind its sister disciplines (such as...

Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volume 1
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volume 1
The aim of Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms is to present recent developments in cell survival and apoptotic pathways and their involvement in human diseases, such as cancers and neurodegenerative disorders. This requires an integration of knowledge from several fields of research, including...
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