Herpes zoster is a serious neurocutaneous disease which has been underestimated
in terms of its burden, particularly in the elderly population. The
overall incidence of herpes zoster in Europe is about 3 per 1,000 people and
more than 10 per 1,000 people per year aged more than 80 years. Due to the
growing life expectancy of the...
This is a comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The book consists of a general part dealing with themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. The second part includes the...
The wireless industry is in the midst of a fundamental shift from providing voice-only services to offering customers an array of multimedia services, including a wide variety of audio, video and data communications capabilities. Future wireless networks will be integrated into every aspect of daily life, and therefore could affect our life...
A panel of senior clinicians critically reviews the many forms of status epilepticus (SE), their causes, manifestations, methods of diagnosis, and appropriate treatments. The emphasis is on the disease as encountered by the clinician in the field and the importance of correct recognition and diagnosis. The authors provide for each form of SE...
The tumor necrosis factor/receptor [TNF/TNFR] superfamily consists of more than 20 transmembrane proteins with conserved N-terminal cysteine-rich domains [CRDs] in the extracellular ligand binding region. Members have wide tissue distribution and play important roles in biological processes such as lymphoid and neuronal development, innate...
The year 2006 is the centenary of Alois Alzheimer’s presentation to a meeting of German
psychiatrists held in Tübingen, Germany. In 1906, Alzheimer described the results of his
studies on a female patient known as Auguste D., who had suffered from a progressive presenile
dementia. In 1907, Alzheimer published this study in...
The second edition of Adhesion Protein Protocols combines traditional techniques with cutting-edge and novel techniques that can be adapted easily to different molecules and cell types. The topics discussed include novel techniques for studying cell-cell adhesion, neutrophil chemotaxis, in vitro assays used to study leukocyte migration...
The goals of chemotherapy (and radiotherapy) are to eliminate tumor cell targets by
promoting cell death. In recent years, a major focus has been placed on programmed
cell death or apoptosis as the primary mechanism of cell killing. However, tumor
cells may respond to various forms of treatment in diverse ways, only some of which...
As our world continues to evolve, the field of regenerative medicine follows
suit. Although many modern day therapies focus on synthetic and natural
medicinal treatments for brain repair, many of these treatments and
prescriptions lack adequate results or only have the ability to slow the progression
of neurological disease or...
The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for...
An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain...
Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos.
