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Gene Therapy for Cancer (Cancer Drug Discovery and Development)
Gene Therapy for Cancer (Cancer Drug Discovery and Development)

The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for...

The Oncogenomics Handbook (Cancer Drug Discovery and Development)
The Oncogenomics Handbook (Cancer Drug Discovery and Development)

An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain...

Status Epilepticus: A Clinical Perspective (Current Clinical Neurology)
Status Epilepticus: A Clinical Perspective (Current Clinical Neurology)

A panel of senior clinicians critically reviews the many forms of status epilepticus (SE), their causes, manifestations, methods of diagnosis, and appropriate treatments. The emphasis is on the disease as encountered by the clinician in the field and the importance of correct recognition and diagnosis. The authors provide for each form of SE...

B Cell Protocols (Methods in Molecular Biology)
B Cell Protocols (Methods in Molecular Biology)

B-lymphocyte development and function remains an exciting area of research for those interested in the physiology and pathology of the immune system in higher animals. While recent advances in genetics and cellular and molecular biology have provided a large spectrum of powerful new experimental tools in this field, it is both time consuming...

Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)
Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)

Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted...

Practical Immunopathology of the Skin (Current Clinical Pathology)
Practical Immunopathology of the Skin (Current Clinical Pathology)

Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and their multiple diagnostic uses in actual clinical case studies. The author presents in an easily digestible form a dictionary of antibody probes, summarizing for each antibody the targeted antigen...

Cancer Chemoprevention: Volume 1: Promising Cancer Chemopreventive Agents (Cancer Drug Discovery and Development) (v. 1)
Cancer Chemoprevention: Volume 1: Promising Cancer Chemopreventive Agents (Cancer Drug Discovery and Development) (v. 1)

A comprehensive reference survey on the identification and development of promising cancer chemopreventive agents that will help stimulate further novel research and new approvable drugs. For each agent, the authors review the relevant mechanisms of action, the criteria for populations benefiting from intervention, the safety and...

Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology)
Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology)

Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transd- tion that directly contribute to a loss of this...

Analysis of Growth Factor Signaling in Embryos (Methods in Signal Transduction Series)
Analysis of Growth Factor Signaling in Embryos (Methods in Signal Transduction Series)

Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos.

Focusing on specific pathways...

Cell-Penetrating Peptides:  Processes and Applications
Cell-Penetrating Peptides: Processes and Applications

One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells...

Microbiology For Dummies
Microbiology For Dummies

Microbiology For Dummies (9781119544425) was previously published as Microbiology For Dummies (9781118871188). While this version features a new Dummies cover and design, the content is the same as the prior release and should not be considered a new or updated product.

Microbiology is the study...

NanoBioEngineering (Volume 2)
NanoBioEngineering (Volume 2)
Nanodelivery of drugs is an area of growing interest. Some key factors such as small size and high surface area, along with drug loading capability, make these ideal drug delivery systems. These can easily be modified to cater to diverse therapeutic and diagnostic applications. Nanoparticles bridge the gap between biomedical and...
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