Anna Seward and her career defy easy placement into the traditional periods of British literature. Raised to emulate the great poets John Milton and Alexander Pope, maturing in the Age of Sensibility, and publishing during the early Romantic era, Seward exemplifies the eighteenth-century transition from classical to Romantic. Claudia Thomas...
“Anne’s contribution to our understanding of the needs of young people with cancer has been unparalleled and without her extraordinary insights our services would be that much poorer.” From the foreword by Simon Davies , CEO Teenage Cancer Trust
This topical and timely text provides valuable insights...
This is a third edition of the popular book, which presents an overview of the most recent findings in the biology of neutrophils. These cells are critically important for protection against bacterial and viral infections and have been recently demonstrated to be a major contributor to tumor associated immune suppression. In addition,...
An estimated two million Americans alive today have been diagnosed with breast cancer. Each one of them lives with the fear of recurrence, and for good reason: for at least a third of women diagnosed with breast cancer, the disease will eventually spread. When this happens most people assume it means an immediate death sentence. The...
In recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in...
Codes have decided the fates of empires, countries, and monarchies throughout recorded history. Mary, Queen of Scots was put to death by her cousin, Queen Elizabeth, for the high crime of treason after spymaster Sir Francis Walsingham cracked the secret code she used to communicate with her conspirators. And thus the course of British history...
This book is a comprehensive text on the all important psychosocial aspects of cancer in children. Edited by an experienced psycho oncologist and an equally experienced pediatric oncologist, the book brings together an international group of contributors composed of pediatric oncologists and psychologists/psycho oncologists. This unique...
A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity,Volume 2: In Vivo Models, Imaging, and Molecular Regulators contains cutting-edge protocols for classifying tumors...
This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in the athletes. This monograph gathers the results of a five-year research program on ARVC/D...
The Routledge Guidebook to Heidegger’s Being and Time examines the work of one of the most controversial thinkers of the twentieth century. Heidegger’s writings are notoriously difficult, requiring careful reading. This book analyses his first major publication, Being and Time, which to this day remains his most...
Myc controls multiple cellular functions, including cell proliferation, growth, differentiation and death, both directly and indirectly, through its modulation of downstream transcriptional programs. In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc...
With this pioneering approach to the study of international history, T. G. Otte reconstructs the underlying principles, elite perceptions and 'unspoken assumptions' that shaped British foreign policy between the death of Palmerston and the outbreak of the First World War. Grounded in a wide range of public and private archival...