If you are part of a large business or are associated with the federal, state, or local government as an employee or as a contractor, this book has special meaning for you. It uses many federal policies, plans, processes, and standards as references. It uses these references for two reasons: first, they are thorough,...

Have you ever had the chance to decide the fate of another person? What would you do? In the real-life cases presented to you in this book,...

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for...

Tay-Sachs disease is a rare hereditary disease caused by a genetic mutation that leaves the body unable to produce an enzyme necessary for fat metabolism in nerve cells, producing central nervous system degeneration. In infants, it is characterized by progressive mental deterioration, blindness, paralysis, epileptic seizures, and death by age...

From prehistoric times, mankind has looked up at the night sky, and puzzled at the changing positions of the stars. How far away they are is a question that has confounded scientists for centuries. Over the last few hundred years, many scientific careers – and considerable resources – have been devoted to measuring their positions...

Advances in medical technology force us to struggle with new and often gut-wrenching decisions. How do we know when someone is dead and not just in a coma? Should a convicted felon qualify for a new heart? In The Woman Who Decided to Die, novelist and medical ethicist Ronald Munson takes readers to the very edges of medicine, where...

Should the hard questions of philosophy matter to ordinary people? In this down-to-earth, nonhistorical guide, Thomas Nagel, the distinguished author of Mortal Questions and The View From Nowhere, brings philosophical problems to life, revealing in vivid, accessible prose why they have continued to fascinate and baffle...