After reviewing the history of cancer and its impact on the population, Dr. Faguet exposes the antiquated notions that have driven cancer drug development, documents the stagnation in treatment outcomes despite major advances in cancer genomics and growing NCI budgets, and identifies the multiple factors that sustain the status quo. He shows...
Dental students are faced with an array of operative procedures; understanding and the development of competence in their use is demanding. This text aims to detail and justify the basic principles involved in operative procedures with the intention of reinforcing understanding and improving clinical skills. Direct and indirect restorations...
Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that...
This concise drug guide lists 500 substances, such as pharmaceutical drugs, lifestyle drugs, and environmental toxicants, which show documented untoward effects on the male sexual organs and their functions. All substances are listed in user-friendly alphabetical order with a uniform structure throughout the book. Each listing includes...
With the expansion of the Internet and the resulting globalization of
business activity, the scope of the influence of information technology (IT)
has increased significantly. Many innovative business practices are being
enabled by IT. The capacity for integration of information in numeric, text,
voice, and video form will give...
The genesis of this book arose from our educational consultations with many physiotherapy
and occupational therapy colleagues around the world. In the course of presenting
workshops that were primarily focused on problem-based learning (PBL), it
became very clear to us that educators in the rehabilitation sciences were very...
Blood loss in spine surgery is a significant and very common problem connected with all kinds of surgical procedures. An international faculty of authors provide a comprehensive survey on the research and evidence about blood sparing in spine surgery. This publication fills a gap in the spinal literature and provides invaluable data for all...
In the second half of the 20th century innate immune responses of cellular or humoral
type were treated like stepchildren by many immunologists: that is, somewhat
neglected. This disregard turned into an exciting research field over the past several
years and led to the identification of receptor families involved in the recognition...
This publication is organized in an exceptional way: Each chapter introduces several completed clinical trials and provides the original conclusions and discussions of the results. The authors then contribute their own comments and interpretations of the findings, challenging the prevailing belief that serum cholesterol is a mediator of...
Transcranial magnetic stimulation (TMS) was introduced in the mid 1980s in clinical neurophysiology to study the central motor pathways. Research has been exponentially increased since, and many different methods for brain stimulation have been considered during the last decade. This publication focuses on transcranially applied, non- or...
Fillers in Aesthetic Medicine is an excellent and comprehensive overview on the clinical use of fillers in aesthetic medicine. It is designed to assist dermatologists as well as plastic surgeons in the aesthetic medical treatment of their patients.
Based on evidence-based medicine guidelines, the first part of the book describes...
Considerable evidence indicates that the U.S. is falling behind when it comes to innovation. In part, this shift stems from the globalization of research and the advancement of other nations. But, it also arises from a widespread failure to adapt to the competitive environment generated by the evolution of science and technology.
The...
