The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological...

This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice.
Organized by the distinctive ataxia disorders, their pathogenesis, and...

The only source on the subject to offer both an overview and a disease-based approach, this reference text spans the wide array of technical, methodological, regulatory, and ethical issues related to pharmacogenetics and stresses the impact of pharmacogenetic data on patient care and management. Providing expertly selected references, tables,...

• Design a successful solution to deliver Windows desktops and applications as a service
• Provide redundancy for components and design a backup solution and disaster recovery plan to protect...

There are always difficulties in making machines that learn from experience. Complete information is not always available—or it becomes available in bits and pieces over a period of time. With respect to systemic learning, there is a need to understand the...

This workbook is packed with hands-on exercises and practical...

Previous studies have looked at the contribution of information technology and network theory to the art of warfare as understood in the broader sense. This book, however, focuses on an area particularly important in understanding the significance of the information revolution; its impact on strategic theory. The purpose of the book is to...

In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry....