This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I Conference in 2006. Written by experts in the field, it addresses a critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that these...
Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being targeted directly with rationally designed inhibitors. Apart from monoclonal antibodies, small molecule therapeutics such as oncogenic protein...
Pediatric brain tumors are a tremendous challenge for the treating physician. Their diverse biological behaviors, in the unique context of the developing nervous system, require fl exible and tailored treatment plans. In the last 20 years, there has been an exponential increase in our understanding of the molecular and genetic basis of human...
This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in...
The importance of the cultural context to health outcomes has only recently become a central concern and a part of the biomedical literature.1-3 A medical encounter is an interpersonal interaction occurring in and influenced by one or more cultural contexts. Ideally, this communication is the seed from which the relationship between the...
This book provides a practical guide to the use of novel and conventional anticoagulants for a variety of medical conditions and patients profiled. It reviews data for selecting the most appropriate medication for a given presentation based on a patient’s background while highlighting current best practices. Chapters discuss...
In 2011 many computer users were exploring the opportunities and the benefits of the massive parallelism offered by heterogeneous computing. In 2000 the Khronos Group, a not-for-profit industry consortium, was founded to create standard open APIs for parallel computing, graphics and dynamic media. Among them has been OpenCL, an open system...
It is the objective of this review to introduce the reader to the current status of
organometallic chemistry, oriented towards the development of novel 99mTc-based imaging
agents. This type of inorganic chemistry has nowadays become part of so-called bioorganometallic
chemistry.
This is a comprehensive guide to cervical cancer for nurses. It is a practically-based text for clinical nurses who wish to consolidate and update their knowledge of cervical cancer. It is concise, containing comprehensive information for general practice together with useful references to facilitate more in-depth study. Thus it provides an...
A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine’s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN...
This volume is an updated reference book for medical dosimetry. It evolved from the book Radiation Dosimetry Instrumentation and Methods (CRC Press, 1991) published 10 years ago, which contains many of the basic facts of radiation dosimetry techniques. The present book contains developments in the last decade, mainly for medical dosimetry....
Hepatocellular carcinoma (HCC) used to be regarded as a rare disease.
The increasing numbers of chronic hepatitis C virus carriers in the United
States and subsequent increased incidence of HCC seen in most large
medical centers means that it is no longer an uncommon disease for most
gastroenterologists or oncologists to...
