Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis. They discuss the means by which these immune functions may be protected or restored in order to more effectively support the process of tumor rejection in situ. Cutting-edge techniques are outlined with the capacity to monitor the strength and quality of patients' immune responses using immunocytometry, MHC-peptide tetramers combined with apoptosis assay, ELISPOT assay, and detection of MHC-TAA peptide complexes on tumor cells.
Python Programming On Win32 : Help for Windows Programmers
This book is about using Python to get jobs done on Windows.
We hope by now you have heard of Python, the exciting object-oriented scripting language that is rapidly entering the programming mainstream. Although Python is perhaps better known on the Unix platform, it offers a superb degree of integration with the Windows...
Explore the new features added to the core Docker Engine to make multi-container orchestration easy
Leverage tools such as Docker Machine, Swarm, Compose, and third-party tools such as Kubernetes, Mesosphere, and CoreOS to orchestrate containers
Use Docker Compose with Swarm and
The Accountable Organization : Reclaiming Integrity, Restoring Trust This book shows how to identify an organization's values and purpose, integrate them into a strategic plan, and develop a focused road map for execution that provides clarity, defines performance standards, and much more.
Recent history of excess and misdeed to the contrary, being principled in business and making a profit are not...