At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in cancer. In addition, this book will offer a comprehensive basic and clinical...

There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental...

Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The...

Differential Diagnosis in Neurology grew out of the author's daily morning reports with neurology residents and the examination of patients in front of colleagues over the last 30 years. The essence of 'differential diagnosis' is 'splitting' rather than 'lumping'. It requires bringing knowledge to the table and...

In recent years the pace of research in prostate cancer has increased dramatically. Creative ideas in combination with new and emerging technologies have led to an explosion of discovery. These types of advances in prostate cancer research presage an era of new treatment strategies based on an understanding of the cellular and molecular...

Michael H. Torosian, MD, and a panel of physicians and clinical researchers critically synthesize the wide variety of treatment options available to create a state-of-the-art reference for the management of breast cancer patients. Writing from a multidisciplinary perspective, these authoritative contributors review in the light of the most...

This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer. It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity....

This publication is a landmark work commemorating the centennial of Alois Alzheimer's discovery of what would be known as Alzheimer's disease (AD). The centennial of Alois Alzheimer's original description of the disease that would come to bear his name offers a vantage point from which to commemorate the seminal discoveries in the...

Recent research and clinical work have demonstrated that the rapid urologic innovation in minimally invasive treatment is creating exciting new horizons in endourology. This sixth volume in the series Recent Advances in Endourology brings that knowledge to a wider audience, focusing on the new concept of endourooncology, which is the...

This volume discusses radiotherapy and its role in the treatment of benign diseases. Its intent is to broaden the application of radiotherapy beyond malignancy to treat a range of clinical concerns, from minor skin problems to life-threatening arterial disease. In addition, it aims to encourage medical practitioners to consider the benefits...