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Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)
Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional...

Pharmacotherapy of Asthma (Lung Biology in Health and Disease)
Pharmacotherapy of Asthma (Lung Biology in Health and Disease)

Standing as the only text focused on the pharmaceutical treatment of asthma, this reference details the pharmacology, mechanisms of action, efficacy, and safety of every drug currently used in the management and care of asthma patients. Internationally renowned authorities cover published practice guidelines, treatment plans, pharmacologic...

Goldfrank's Toxicologic Emergencies
Goldfrank's Toxicologic Emergencies
The #1 reference in the field for the last quarter of a century, Goldfrank's Toxicologic Emergencies, Eighth Edition, has been completely updated to equip emergency physicians with today's most authoritative guide to clinical toxicology. The book presents unsurpassed coverage of all aspects of toxicologic emergencies_from pharmacology and clinical...
Numerical Methods for the Life Scientist: Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB
Numerical Methods for the Life Scientist: Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB

Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical...

Bioactives in Fruit: Health Benefits and Functional Foods
Bioactives in Fruit: Health Benefits and Functional Foods

For centuries we have known that fruit is important for health, but we are only just beginning to fully understand why.  Bioactives in Fruit: Health Benefits and Functional Foods aims to summarise some of our current knowledge on the bioactive compounds that are associated with the health benefits of...

The Effects of Estrogen on Brain Function
The Effects of Estrogen on Brain Function

This timely volume reviews current data on the effects of estrogen on the central nervous system, highlighting clinical aspects of this topic. Experts from the fields of psychiatry, pharmacology, neurology, and geriatrics collaborate to clarify the known risks and benefits of hormone therapy and explore questions that remain to be...

The Adrenergic Receptors in the 21st Century (The Receptors)
The Adrenergic Receptors in the 21st Century (The Receptors)
Our understanding of adrenergic function has advanced considerably in the 15 years since three adrenergic receptor books were published in The Receptors series. In the late 1980s, many of the adrenergic subtypes had not yet been cloned. Most of the studies during that time focused on traditional pharmacological approaches in...
Basic Concepts in Biochemistry: A Student's Survival Guide
Basic Concepts in Biochemistry: A Student's Survival Guide

This second edition continues to innovatively review the toughest concepts in biochemistry for maximum comprehension in a short period of time. Unlike conventional texts or review books that stress memorizing facts, BASIC CONCEPTS stresses the mastering of fundamental concepts, so that the reader truly comprehends the material and feels...

Drug Use and Abuse: A Comprehensive Introduction
Drug Use and Abuse: A Comprehensive Introduction

Packed with the latest data and research, the powerful new DRUG USE AND ABUSE: A COMPREHENSIVE INTRODUCTION, 8e delivers a thorough, interdisciplinary survey of all aspects of drug and alcohol abuse. The text draws from the many disciplines of history, law, pharmacology, political science, social work, counseling, psychology, sociology, and...

Nonlinear Regression with R (Use R!)
Nonlinear Regression with R (Use R!)
This book is about nonlinear regression analysis with R, in particular, how to use the function nls() and related functions and methods.

Range of the book

Nonlinear regression may be a confined and narrow topic within statistics. However, the use of nonlinear regression is seen in many applied
...
Advances in Chromatographic Techniques for Therapeutic Drug Monitoring
Advances in Chromatographic Techniques for Therapeutic Drug Monitoring

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for...

Essential Anesthesia: From Science to Practice (Cambridge Medicine)
Essential Anesthesia: From Science to Practice (Cambridge Medicine)

Essential Anesthesia is a concise, accessible introduction to anesthetic practice. Now in its second edition, it provides a thorough overview of the science and practice of anesthesia. Part I describes the evaluation of the patient, the different approaches to anesthesia, and the post-operative care of the patient in pain. Part II introduces...

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