Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can...

Expert laboratorians noted for their optimized methods describe in step-by-step detail how to successfully carry out tissue-based laser microdissection in their own laboratory using the different systems available and to apply a wide range of sophisticated molecular technologies to the microdissected tissue samples. Highlights include gene...

.NET parallel extensions brings the power of parallel and asynchronous programming to a much wider developer audience than ever before. This book will give a developer with no multithreaded development experience the ability to write highly scalable parallel applications that take advantage of modern multicore processors.If you are an...

Expert PL/SQL Practices is a book of collected wisdom on PL/SQL programming from some of the best and the brightest in the field. Each chapter is a deep-dive into a specific problem, technology, or feature set that you’ll face as a PL/SQL programmer. Each author has chosen their topic out of the strong belief that what they...

You can have the best coders in the world working in your teams, but if your project management isn’t up to scratch, your project is almost certain to be delayed, to come in over budget, and in some cases to fail entirely. By taking precise control of your application development process, you can make changes, both large and small,...

Pro SQL Server 2012 Integration Services teaches how to take advantage of the powerful extract, transform, and load (ETL) platform included with Microsoft SQL Server 2012. You’ll learn to build scalable, robust, performance-driven enterprise ETL solutions that save time and make money for your company. You'll learn to...

readers grasp the basic concepts, principles, methodologies, best practices, queueing theories, and profiling tools associated with optimizing software performance and...

NHibernate 3 Beginner's Guide examines all of the topics required to get a functional data-access layer implemented while writing the least amount of code possible, presenting options along the way to handle particular edge cases or situations as they arise. The book begins with an introduction to NHibernate 3 and then moves on to...