Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different...

Numerical Methods in Engineering with Python, 2nd Edition is a text for engineering students and a reference for practicing engineers, especially those who wish to explore Python. This new edition features 18 additional exercises and the addition of rational function interpolation. Brent's method of root finding was replaced by...

Society today, writes Stephen Post, is "hypercognitive": it places inordinate emphasis on people's powers of rational thinking and memory. Thus, Alzheimer disease and other dementias, which over an extended period incrementally rob patients of exactly those functions, raise many dilemmas. How are we to view―and...

Plato's account of the tripartite soul is a memorable feature of dialogues like the Republic, Phaedrus and Timaeus: it is one of his most famous and influential yet least understood theories. It presents human nature as both essentially multiple and diverse - and yet somehow also one - divided into a fully human 'rational' part, a...

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Modern crystallographic methods originate from the synergy of two main research streams, the small-molecule and the macro-molecular streams. The first stream was able to definitively solve the phase problem for molecules up to 200 atoms in the asymmetric unit. The achievements obtained by the macromolecular stream are also impressive. A huge...

Over the last decade the increasing phenomenon of suicide terrorism has raised questions about how it might be rational for individuals to engage in such acts. This book examines a range of different forms of political self-sacrifice, including hunger strikes, self-burning and non-violent martyrdom, all of which have taken place in resistance...

Engineering Economy is intended to serve as a text for classroom instruction in undergraduate, introductory courses in Engineering Economics. It also serves as a basic reference for use by practicing engineers in all specialty areas (e.g., chemical, civil, computer, electrical, industrial, and mechanical engineering)....