Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being targeted directly with rationally designed inhibitors. Apart from monoclonal antibodies, small molecule therapeutics such as oncogenic protein...

Nutrition is one of the most important factors that impact health in all areas of the lifecycle. Pregnant women need adequate food and health care to deliver a healthy baby who has a good birth weight and a fighting chance for survival. In many regions of the world, the infant mortality rate is very high, meaning that many infants will not live...

This is the first Digital Imaging and Communications in Medicine (DICOM) book to introduce this complex imaging standard from a very practical point of view. It is aimed at a broad audience of radiologists, clinical administrators, information technologists, and digital medicine practitioners. It provides a gradual, down-to-earth introduction...

Today DBAs are expected to deploy and manage large databases with quality service and little to no downtime. The DBA's main focus is on increasing productivity and eliminating idle redundancy throughout the enterprise. However, there is no magic set of best practices or hard and fast rules that DBAs need to follow, and this can make life...

Finally, from the author of Compost, fascinating information and advice on handling weeds - how to recognize them, how to control them, and how to exploit them. The first step is to know your enemy, so weeds are identified and the survival strategies of various types is explained to enable you to get rid of them more easily. Finally,...

Covering cloud computing from what the business leader needs to know, this book describes how IT can nimbly ramp up revenue initiatives, positively impact business operations and costs, and how this allows business leaders to shed worry about technology so they...

Once upon a time, Unix came with only a few standard utilities. If you were lucky, it included a C compiler. When setting up a new Unix system, you’d have to crawl the Net looking for important software: Perl, gcc, bison, flex, less, Emacs, and other utilities and languages. That was a lot of software to download through a 28.8-Kbps...

Our world faces an unprecedented energy crisis. Fuel shortages, skyrocketing energy prices, climate change, nuclear contamination, catastrophic oil spills and energy wars define the global scenario. The nonrenewable energy path of oil, natural gas, coal and nuclear is headed for a dead-end at an accelerated speed. In our race for survival we...

The book begins with...

Genetic algorithms are founded upon the principle of evolution, i.e., survival of the fittest. Hence evolution programming techniques, based on genetic algorithms, are applicable to many hard optimization problems, such as optimization of functions with linear and nonlinear constraints, the traveling salesman problem, and problems of...

Sequencing and scheduling is a formof decision-making that plays a crucial role in manufacturing and service industries. In the current competitive environment effective sequencing and scheduling has become a necessity for survival in the market-place. Companies have to meet shipping dates that have been committed to customers, as failure to...