One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells...

Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular...

This exceptional new resource introduces the fundamentals...

Meet the learning needs of today’s students with a brand-new style of textbook—designed to excite your students’ interest in clinical chemistry! Organized almost entirely around organ systems—to parallel the way physicians order tests—this groundbreaking text teaches the concepts and principles...

This accessible work is the first in more than seventy-five years to discuss the many roles of adrenaline in regulating the "inner world" of the body. David S. Goldstein, an international authority and award-winning teacher, introduces new concepts concerning the nature of stress and distress across the body's regulatory...