Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use. Specific...

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for...

In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book discusses in depth the potential of...

Worldwide, there are an estimated 232, 000 new cases of pancreatic cancer annually. In the United States, it is the fourth leading cause of cancer death, and approximately 30,000 people die of pancreatic cancer each year. The disease is difficult to diagnose in its early stages, and most patients have incurable disease by the time they present...

It certainly is gratifying and exciting for me, as coeditor of the two previous editions of this Handbook (i.e., Singer, Murphy, & Tennant, 1993; Singer, Hausenblas, & Janelle, 2001), to realize the impact this type of resource book has had on the field of sport psychology in general, and on so many individuals around the world. These...

Biomedical Image Analysis and Machine Learning...

The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time,...

Aristotle, one of mankind’s greatest thinkers, rooted his basis of human understanding in the notion that universal phenomena can be explained through perception and rationalization. As such, Aristotle conjectured that a 10-pound object should fall through the air 10 times faster than a similar 1-pound object. This, and other intuitive...

The urge to write this book—and it was indeed an urge—arose because of two reasons. The first was the lack of a book that approached patient care from the viewpoint of on-call medical residents. New residents faced with admitting a sick patient in the middle of the night have three priorities: one, a working diagnosis; two, a...

The new Fourth Edition of Bacterial Infections of Humans reflects a decade of important discoveries, technological progress, and valuable new therapies as well as emerging and reemerging infections, resistant strains of bacteria, and threats of bioterrorism. It offers accessible, up-to-date information across the range of disease...

The focus of the book is on how fundamental statistical and data mining approaches...