Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological...

From the Daily Mail's claim of Britain being named ‘Yob Capital of Europe’, to the headline in The Times of ‘Tearaway given ASBO at 10’, the subject of anti-social behaviour has been given a huge amount of political, social, media, public policy and academic interest in recent years.

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This book addresses the continuing controversy over the potential impact of genetically modified (GM) crops in developing countries. Supporters of the technology claim it offers one of the best hopes for increasing agricultural production and reducing rural poverty, while opponents see it as an untested intervention that will bring corporate...

In the first part, the book investigates the current features of...

We’ve all...

The finite element method (FEM) is a computational technique for solving problems which are described by partial differential equations or which can be formulated as functional minimization. The FEM is commonly used in the design and development of products, especially where structural analysis is involved. The simple object model of the...

Computational techniques based on simulation have now become an essential part of the statistician's toolbox. It is thus crucial to provide statisticians with a practical understanding of those methods, and there is no better way to develop intuition and skills for simulation than to use simulation to solve statistical problems. Introducing...