The author successfully developed novel anti-HIV PD 404182 derivatives that exhibited submicromolar inhibitory activity against both HIV-1 and HIV-2. His thesis is in three parts. The first part expounds efficient methods for the synthesis of tricyclic heterocycles related to PD 404182 based on the...

This book examines distributed video coding (DVC) and multiple description coding (MDC), two novel techniques designed to address the problems of conventional image and video compression coding. Covering all fundamental concepts and core technologies, the chapters can also be read as independent and self-sufficient, describing each...

The idea of infinity plays a crucial role in our understanding of the universe, with the infinite spacetime continuum perhaps the best-known example - but is spacetime really continuous? Throughout the history of science, many have felt that the continuum model is an unphysical idealization, and that spacetime should be thought of as...

Presents a detailed study of the major design components that constitute a top-down decision-tree induction algorithm, including aspects such as split criteria, stopping criteria, pruning and the approaches for dealing with missing values. Whereas the strategy still employed nowadays is to use a 'generic' decision-tree induction...

​​​​Describing novel mathematical concepts for recommendation engines, Realtime Data Mining: Self-Learning Techniques for Recommendation Engines features a sound mathematical framework unifying approaches based on control and learning theories, tensor factorization, and hierarchical methods. Furthermore, it...

This book builds a novel bridge from molecular research to clinical therapy. This approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes...

This book discusses the question of how information systems can be used and managed in a responsible manner. Normative problems such as intellectual property, privacy, power distribution, etc., are at the heart of many of the problems faced by users and managers of information systems. Responsible Management of Information Systems...