There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental...

This book will introduce contributions, both methodological and technical, that have been made and are currently in progress in the field of computational biology as a resource in cancer research and oncology. This volume will illustrate the tools used in this area through a wide range of timely applications in genetics, genomics, and biomedical...

This book is a collection of six articles arising from the meeting of the NATO Advanced Study Institute (ASI) ''Combinatorial Optimization: Methods and Applications,'' which was held at the University of Montreal in June 2006. This ASI consisted of seven series of five one-hour lectures and one series of four one-hour...

Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular...

Brain tumors have a longstanding reputation for being intractable to therapy, and with evidence suggesting that the incidence of some brain tumors is increasing, this has become the most feared cancer. However, with improvements in imaging technologies, radiation therapy and chemotherapy , as well as a greater knowledge of the genetic causes...

Leading oncologists, hematologists, and nephrologists comprehensively review the role of HGFs in clinical practice, explain the molecular basis of their effects, and consider potential future developments. The authors focus on the use of HGFs in oncology, describing their cutting-edge application to patients with lung cancer, Hodgkin's...

Analyzing a key cause of infectious morbidity in immunosuppressed and immunocompromised patients, this source spans the most recent strategies to improve and expedite the diagnosis, identification, and treatment of fungal infections. With authoritative contributions from experienced clinicians in the field, this reference tracks developments...

Recent research and clinical work have demonstrated that the rapid urologic innovation in minimally invasive treatment is creating exciting new horizons in endourology. This sixth volume in the series Recent Advances in Endourology brings that knowledge to a wider audience, focusing on the new concept of endourooncology, which is the...

Emphasizing practical technique over underlying physics, this book discusses the use of PET/CT imaging in lung, lymphoma, esophageal, colorectal, head/neck and melanoma, and tumors of the reproductive system. Each chapter offers a summary of the appropriate staging system, and a full chapter is devoted to the range of normal PET/CT...