Although depression is the most common presentation of bipolar disorder, correct diagnosis generally requires a history of mania and thus presents a formidable challenge. This book provides clinicians with the necessary guidance to distinguish this illness and pursue an appropriate therapeutic course. It brings together a team of clinical...
Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially...
This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future...
Considerable evidence indicates that the U.S. is falling behind when it comes to innovation. In part, this shift stems from the globalization of research and the advancement of other nations. But, it also arises from a widespread failure to adapt to the competitive environment generated by the evolution of science and technology.
The...
Despite tremendous advances in the understanding of the sensory nervous system which have accompanied the recent explosive growth of the neurosciences, rema- ably few innovative medicines directed towards pain and inflammation are ava- able. Indeed, many patients are still prescribed analgesic and anti-inflammatory medications that were...
Engineering Economy is intended to serve as a text for classroom instruction in undergraduate, introductory courses in Engineering Economics. It also serves as a basic reference for use by practicing engineers in all specialty areas (e.g., chemical, civil, computer, electrical, industrial, and mechanical engineering)....
In their timely and important book, ELIMINATING HEALTHCARE
DISPARITIES IN AMERICA: BEYOND THE IOM REPORT, Dr. Richard
Allen Williams and colleagues provide a comprehensive analysis of the
causes and potential solutions to eliminating health care disparities. Their
work is timely, because little progress has been made in reducing...
The year 2006 is the centenary of Alois Alzheimer’s presentation to a meeting of German
psychiatrists held in Tübingen, Germany. In 1906, Alzheimer described the results of his
studies on a female patient known as Auguste D., who had suffered from a progressive presenile
dementia. In 1907, Alzheimer published this study in...
In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach...
In a previous publication, the authors attempted to cover not only topical
issues but also difficult problems that might confront recently appointed
trainees in the decisions they make that confront these individuals in their
future practices.
Since that time, much of the thrust of coloproctology and government...
The rheumatic diseases in children range from affecting a very isolated part of the body to including almost every organ and body system. Much progress has been made in the field of rheumatology over the past decade and this book provides a small didactic text, giving clear unambiguous guidance on the best clinical practice. With full colour...
